Detail
RLID: | RLID00001945 |
RNA Symbol: | Tmevp3 |
RNA Category: | lncRNA |
Organism: | Mus musculus |
Aliase: | NeST |
Subcellular Localization: |
Localization | Tissue | Validated Method | PMID |
Nucleus | T cell | RT-PCR | 23415224 |
Description: We hypothesized that, like several lncRNAs, NeST RNA affects IFN-纬 accumulation at the transcriptional level by interacting with chromatin modification complexes. Consistent with this idea, most of the NeST RNA in either congenic or transgenic mice was found in the nuclear fraction of CD8+ T cells, co-fractionating with unspliced, but not spliced, actin mRNA (Fig. 6A). |