Detail
| RLID: | RLID00002282 |
| RNA Symbol: | Actb |
| RNA Category: | mRNA |
| Organism: | Mus musculus |
| Aliase: | Actx, E430023M04Rik, beta-actin |
| Homology: | ACTB (Gallus gallus), ACTB (Homo sapiens) |
| Subcellular Localization: | |
| Localization | Tissue | Validated Method | PMID |
| Growth cone | Motoneuron | In situ hybridization | 14623865 |
| Description: Overexpression of Smn or its binding partner, heterogeneous nuclear ribonucleoprotein (hnRNP) R, promotes neurite growth in differentiating PC12 cells. Reduced axon growth in Smn-deficient motoneurons correlates with reduced å°¾-actin protein and mRNA staining in distal axons and growth cones.Overexpression of Smn or its binding partner, heterogeneous nuclear ribonucleoprotein (hnRNP) R, promotes neurite growth in differentiating PC12 cells. Reduced axon growth in Smn-deficient motoneurons correlates with reduced å°¾-actin protein and mRNA staining in distal axons and growth cones. | |||
Other Subcellular Localization:
| RLID | Localization | Tissue | Validated Method | PMID |
| RLID00002280 | Cytoplasm | Bone marrow Macrophage | Next-generation sequencing | 22817891 |
| RLID00002281 | Exosome | Mast cell | Microarray | 17486113 |
| RLID00002283 | Endoplasmic reticulum | MIN6 cell | Northern blot | 15972000 |
| RLID00002284 | Cytosol | MIN6 cell | Northern blot | 15972000 |
| RLID00002285 | Dendrite | Hippocampus | In situ hybridization | 16317045 |
| RLID00002286 | Ribosome | S/S MEF cell | RT-PCR | 18195013 |
| RLID00002287 | Dendrite | Neuron | Fluorescence in situ hybridization | 18539120 |
| RLID00002288 | Cell leading edge | Fibroblast | Fluorescence in situ hybridization | 22832165 |
| RLID00002289 | Axon | Soma | qRT-PCR | 24381269 |
| RLID00002290 | Cell leading edge | MEF cell | Florescence micrograph | 26140598 |
| RLID00002291 | Perinuclear | MEF cell | Florescence micrograph | 26140598 |
| RLID00002292 | Axon | Motoneuron | In situ hybridization|qRT-PCR | 26464439 |
| RLID00002293 | Somatodendritic compartment | Motoneuron | In situ hybridization|qRT-PCR | 26464439 |
| RLID00002294 | Lamellipodium | Migrating cell | qRT-PCR | 18451862 |
| RLID00002295 | Cell leading edge | Migrating cell | qRT-PCR | 18451862 |