Detail
| RLID: | RLID00002290 |
| RNA Symbol: | Actb |
| RNA Category: | mRNA |
| Organism: | Mus musculus |
| Aliase: | Actx, E430023M04Rik, beta-actin |
| Homology: | ACTB (Gallus gallus), ACTB (Homo sapiens) |
| Subcellular Localization: | |
| Localization | Tissue | Validated Method | PMID |
| Cell leading edge | MEF cell | Florescence micrograph | 26140598 |
| Description: Next,we focused on the interaction in the cytoplasm, more specifically, the leading edge (Figure 2F, circle) and perinuclear regions (Figure 2F, square). In immortalized MEFs (Figures 2H and 2I), we found that ZBP1 bound b-actin mRNAs almost equally in both compartments (p > 0.1) (Figure 2J). It has been shown that b-actin mRNA localizes to the leading edge of primary fibroblasts. | |||
Other Subcellular Localization:
| RLID | Localization | Tissue | Validated Method | PMID |
| RLID00002280 | Cytoplasm | Bone marrow Macrophage | Next-generation sequencing | 22817891 |
| RLID00002281 | Exosome | Mast cell | Microarray | 17486113 |
| RLID00002282 | Growth cone | Motoneuron | In situ hybridization | 14623865 |
| RLID00002283 | Endoplasmic reticulum | MIN6 cell | Northern blot | 15972000 |
| RLID00002284 | Cytosol | MIN6 cell | Northern blot | 15972000 |
| RLID00002285 | Dendrite | Hippocampus | In situ hybridization | 16317045 |
| RLID00002286 | Ribosome | S/S MEF cell | RT-PCR | 18195013 |
| RLID00002287 | Dendrite | Neuron | Fluorescence in situ hybridization | 18539120 |
| RLID00002288 | Cell leading edge | Fibroblast | Fluorescence in situ hybridization | 22832165 |
| RLID00002289 | Axon | Soma | qRT-PCR | 24381269 |
| RLID00002291 | Perinuclear | MEF cell | Florescence micrograph | 26140598 |
| RLID00002292 | Axon | Motoneuron | In situ hybridization|qRT-PCR | 26464439 |
| RLID00002293 | Somatodendritic compartment | Motoneuron | In situ hybridization|qRT-PCR | 26464439 |
| RLID00002294 | Lamellipodium | Migrating cell | qRT-PCR | 18451862 |
| RLID00002295 | Cell leading edge | Migrating cell | qRT-PCR | 18451862 |