Detail
| RLID: | RLID00003371 |
| RNA Symbol: | En1 |
| RNA Category: | mRNA |
| Organism: | Mus musculus |
| Aliase: | En-1, Mo-en.1 |
| Homology: | EN1 (Homo sapiens ) |
| Subcellular Localization: | |
| Localization | Tissue | Validated Method | PMID |
| Dendrite | Ventral midBrain | In situ hybridization | 17399993 |
| Description: Here we report the presence of Engrailed protein and En1 mRNA in proximal dendrites of these neurons and of En1 mRNA in ventral midbrain synaptoneurosomes. In contrast, the mRNA of En2 and HPRT (hypoxanthine phosphoribosyltransferase; a well-expressed soma-restricted mRNA) in the SN and VTA (Figs. 1G-J) are confined to the cell body, which confirms the specificity of En1 mRNA dendritic staining. This finding, along with the absence of En2 mRNA in SNSs, confirms the in situ hybridization data and establishes that En1 mRNA is transported into the dendrites of ventral midbrain neurons. | |||
Other Subcellular Localization:
| RLID | Localization | Tissue | Validated Method | PMID |