Detail
RLID: | RLID00004258 |
RNA Symbol: | Ins2 |
RNA Category: | mRNA |
Organism: | Mus musculus |
Aliase: | AA986540, Ins-2, InsII, Mody, Mody4 |
Subcellular Localization: |
Localization | Tissue | Validated Method | PMID |
Endoplasmic reticulum | MIN6 cell | Northern blot | 15972000 |
Description: In conclusion, our results provide evidence that the selective recruitment of proinsulin mRNA to the ER, together with increases in the rate of initiation are important mediators of glucose-stimulated proinsulin synthesis in pancreatic beta-cells. |