Detail
| RLID: |
RLID00005831 |
| RNA Symbol: |
Xist |
| RNA Category: |
lncRNA |
| Organism: |
Mus musculus |
| Aliase: |
A430022B11, AI314753 |
| Subcellular Localization: |
| Localization |
Tissue |
Validated Method |
PMID |
| Nucleus |
Bone marrow Macrophage |
Next-generation sequencing |
22817891 |
|
Description: Cluster 7, for example, contains abundant transcripts in the chromatin, with much lower transcript levels in the nucleoplasm and cytoplasm relative to the other clusters. This cluster is dominated by annotated and unannotated non-coding transcripts and miRNA precursors. (The analysis excluded transcripts shorter than 400 nucleotides and therefore excluded mature miRNAs and many miRNA precursors.) Some non-coding RNAs, such as Xist, are highly enriched in the chromatin because they function at this location (Figure S2). Examples of other non-coding RNAs in Cluster 7 are Neat1 and Malat1/Neat2 (Figure S2). Further mining of the data sets may provide insights into the subcellular locations at which many non-coding RNAs function. Cluster 7 also includes transcripts from constitutive protein-coding genes that may be highly unstable and therefore present at low levels in the cytoplasm (e.g. Leng8 in Figure S2).
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Other Subcellular Localization: