Detail

RLID: RLID00008689
RNA Symbol: SNORA73B
RNA Category: snoRNA
Organism: Homo sapiens
Aliase: 105A, E1c, RNU105A, RNU17B, U17B
Sequence:
Subcellular Localization:
Localization Tissue Validated Method PMID
Nucleus Colon cancer cell Next-generation sequencing 24393600
Description: The RNA composition of the subcellular fractions differs significantly from each other, but lncRNAs are found in all locations. A subset of specific lncRNAs is enriched in the nucleus but surprisingly the majority is enriched in the cytosol and in ribosomal fractions. The ribosomal enriched lncRNAs include H19 and TUG1. Most studies on lncRNAs have focused on the regulatory function of these transcripts in the nucleus. We demonstrate that only a minority of all lncRNAs are nuclear enriched. Our findings suggest that many lncRNAs may have a function in cytoplasmic processes, and in particular in ribosome complexes. Data were collected from additional file 5: Table showing the normalized read counts for each cluster in Figure 4A.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00008690 Nucleus HeLa cell Northern blot 9671460
RLID00008691 Nucleus HeLa cell Next-generation sequencing 25203660
RLID00008692 Nucleolus HeLa cell Next-generation sequencing 25203660
RLID00008693 Nucleus Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00008694 Cytoplasm Nasopharyngeal carcinoma cell Next-generation sequencing 20498841