Detail
| RLID: |
RLID00009351 |
| RNA Symbol: |
NEAT1 |
| RNA Category: |
lncRNA |
| Organism: |
Homo sapiens |
| Aliase: |
LINC00084, NCRNA00084, TncRNA, VINC |
| Subcellular Localization: |
| Localization |
Tissue |
Validated Method |
PMID |
| Nucleus |
HeLa cell |
Immunoblotting|RT-PCR |
23835137 |
|
Description: NEAT1_2 lncRNA may act as a scaffold of RNAs and RNA binding proteins in the nuclei of ALS motor neurons, thereby modulating the functions of ALS-associated RNA-binding proteins during the early phase of ALS. These findings provide the first evidence of a direct association between paraspeckle formation and a neurodegenerative disease, and may shed light on the development of novel therapeutic targets for the treatment of ALS.
|
Other Subcellular Localization: