Detail
| RLID: | RLID00010991 |
| RNA Symbol: | grk |
| RNA Category: | mRNA |
| Organism: | Drosophila melanogaster |
| Aliase: | Dmel_CG17610, CG17610, CT32746, DmelCG17610, GRK, Grk, s-Grk |
| Subcellular Localization: | |
| Localization | Tissue | Validated Method | PMID |
| Posterior | Oocyte | In situ hybridization | 24531791 |
| Description: A particularly significant target of dynein-mediated transport is gurken (grk) whose transcript localization is key to establishing the prospective body axes of the future embryo. grk mRNA localizes posteriorly in early oocytes and is translated during stage 5 into a transforming growth factor-a like protein that signals to overlying, somatic follicle cells to specify their posterior character. During this stage, the minus-ends of MTs are orientated predominantly toward the oocyte posterior. | |||
Other Subcellular Localization:
| RLID | Localization | Tissue | Validated Method | PMID |
| RLID00010977 | Nucleus | Oocyte | In situ hybridization | 10024878 |
| RLID00010978 | Anterior | Oocyte | In situ hybridization | 10024878 |
| RLID00010979 | Endoplasmic reticulum | Oocyte | In situ hybridization | 10024878 |
| RLID00010980 | Posterior | Embryo | In situ hybridization | 11131516 |
| RLID00010981 | Golgi apparatus | Oocyte|Neuron cell | In situ hybridization | 15385627 |
| RLID00010982 | Endoplasmic reticulum | Oocyte|Neuron cell | In situ hybridization | 15385627 |
| RLID00010983 | Dorsal | Oocyte | In situ hybridization | 16319114 |
| RLID00010984 | Cell cortex | Oocyte | In situ hybridization | 19217894 |
| RLID00010985 | Anterior | Oocyte | In situ hybridization | 24531791 |
| RLID00010986 | Cell cortex | Oocyte | In situ hybridization | 24531791 |
| RLID00010987 | Dorsal | Oocyte | In situ hybridization | 24531791 |
| RLID00010988 | Dorsal | Oocyte | In situ hybridization | 24531791 |
| RLID00010989 | Dorsal | Oocyte | In situ hybridization | 24531791 |
| RLID00010990 | Cytoskeleton | Oocyte | In situ hybridization | 24531791 |
| RLID00010992 | Nucleus | Oocyte | In situ hybridization | 24718986 |
| RLID00010993 | Cytoplasm | Oocyte | - | 26214278 |
| RLID00010994 | Anterior | Embryo | In situ hybridization | 25838129 |