Detail
| RLID: | RLID00012604 |
| RNA Symbol: | TPO |
| RNA Category: | mRNA |
| Organism: | Canis lupus familiaris |
| Subcellular Localization: | |
| Localization | Tissue | Validated Method | PMID |
| Nucleus | Thyroid epithelial cell | In situ hybridization | 8269983 |
| Description: As compared to another thyroid differentiation marker, thyroglobulin mRNA (Pohl et al., J. Cell Biol. 111, 663-672 (1990)), TPO mRNA accumulation differed by the rapidity of its control by cAMP, the pattern of its intercellular heterogeneity, and the unexpected segregation to a perinuclear region, probably the nuclear envelope that constitutes a specialized part of the endoplasmic reticulum. | |||