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Description: The mRNA transcriptome is currently thought to be partitioned between the cytosol and endoplasmic reticulum (ER) compartments by binary selection; mRNAs encoding cytosolic/nucleoplasmic proteins are translated on free ribosomes, and mRNAs encoding topogenic signal-bearing proteins are translated on ER-bound ribosomes, with ER localization being conferred by the signal-recognition particle pathway. Data are collected from Supplemental Data - The gene lists selected by the described GO categories are listed. Gene ID and subcellular distribution values, in log2 as well as fractional ER enrichment are listed.
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