Detail
| RLID: |
RLID00024108 |
| RNA Symbol: |
YPT1 |
| RNA Category: |
mRNA |
| Organism: |
Saccharomyces cerevisiae |
| Aliase: |
YFL038C |
| Homology: |
RAB1A (Homo sapiens
) |
| Subcellular Localization: |
| Localization |
Tissue |
Validated Method |
PMID |
| Cellular bud |
Yeast |
Fluorescence in situ hybridization |
17339339 |
|
Description: As SEC4 mRNA is asymmetrically distributed to the bud prior to nuclear division, similar to ASH1 mRNA, we examined the localization of other POL mRNAs by FISH (Fig. 1B). Endogenous mRNAs encoding the Cdc42 and Rho3 GTPases (31); the Sec1, Sro7, and Sro77 SNARE regulators (23,25); the Sec3 and Exo84 exocyst components (27); and Ypt1, a GTPase involved in ER-Golgi transport, localized at least in part to the buds of G2/M phase cells prior to nuclear division. This pattern was discerned in 鈮?0% of cells for each mRNA examined (Fig. 1B), indicating that these mRNAs were also exported from mother cells. Asymmetric POL mRNA localization correlates with the bud-specific pattern of protein localization seen during cell division.
|
Other Subcellular Localization: