Detail
| RLID: |
RLID00026825 |
| RNA Symbol: |
Alpha-280 |
| RNA Category: |
lncRNA |
| Organism: |
Homo sapiens |
| Subcellular Localization: |
| Localization |
Tissue |
Validated Method |
PMID |
| Cytoplasm |
HeLa cell |
Binding assays |
7867928 |
|
Description: Although alpha-280 is detected among both the cells' nuclear and cytoplasmic RNAs, the great majority of alpha-250 is found in the cytoplasmic subcellular compartment. As judged by its resistance to high concentrations of alpha-amanitin, cell-free transcription of alpha-250 and alpha-280 appears to involve RNA polymerase I. Tissue culture transfection and cell-free transcription experiments demonstrate that alpha-250 and alpha-280 stimulate S14 mRNA transcription, whereas free ribosomal protein S14 inhibits it.
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Other Subcellular Localization: