Detail
| RLID: |
RLID00027496 |
| RNA Symbol: |
hsa-let-7b |
| RNA Category: |
miRNA |
| Organism: |
Homo sapiens |
| Aliase: |
hsa-let-7bL |
| Subcellular Localization: |
| Localization |
Tissue |
Validated Method |
PMID |
| Mitochondrion |
Myoblast |
In situ hybridization |
21637849 |
|
Description: In situ hybridization of pre-mir-302a, pre-let-7b and mir-365, using specific labelled locked nucleic acids and confocal microscopy, demonstrated that these miRNA were localized in mitochondria of human myoblasts. Strikingly, we also observed that two pre-miRNAs, pre-mir302a and pre-let-7b were located within mitochondria surrounding the nucleus (Figures 5E, F). The present study demonstrated for the first time the localization of pre-miRNA (pre-mir-302a, pre-let-7b) and miRNA in human mitochondria isolated from muscular cells.
|
Other Subcellular Localization: