Detail

RLID: RLID00027975
RNA Symbol: hsa-let-7b-5p
RNA Category: miRNA
Organism: Homo sapiens
Aliase: hsa-let-7b
Sequence:
Homology: aae-let-7 (Aedes aegypti), bta-let-7a-5p (Bos taurus)
Network:
Subcellular Localization:
Localization Tissue Validated Method PMID
Microvesicle Seminal Plasma Microarray 23539611
Description: MiRNAs shuttled by SMVs in seminal plasma are potent non-invasive biomarkers to evaluate defects originating from the different organs of the male reproductive tract, including the epididymis (Wang et al., 2011). In order to assess the reversibility of post-vasectomy miRNA sequelae, we investigated whether SMV miRNAs altered by vasectomy could be retrieved in SMVs from normospermic vasovasostomized donors. miRNA microarray profiling performed on SMVs from normal, vasectomized and vasovasostomized donors identified 313 miRNAs whose intensity was above the threshold of detection. Among these miRNAs, 293 were detected in samples from normal donors, 275 in vasectomized donors and 298 in vasovasostomized donors (Fig. 3, Supplementary data, Table SIV). Data are collected from Table S4.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00027956 Circulating Plasma Microarray 22884882
RLID00027957 Circulating Cerebrospinal fluid Next-generation sequencing|RT-PCR 23525801
RLID00027958 Circulating Serum Next-generation sequencing|RT-PCR 23525801
RLID00027959 Circulating Serum Next-generation sequencing 23641832
RLID00027960 Circulating Follicular fluid Microarray 23666971
RLID00027961 Cytoplasm Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00027962 Cytoplasm HeLa cell Microarray 21695135
RLID00027963 Extracellular vesicle HEK293T|HMEC-1|Mononuclear cell Next-generation sequencing 22849433
RLID00027964 Exosome Serum Microarray 18589210
RLID00027965 Exosome Saliva Microarray 19627513
RLID00027966 Exosome Breast cancer cell Microarray 20976003
RLID00027967 Exosome Dendritic cell Microarray 21505438
RLID00027968 Exosome B cell Microarray 21505438
RLID00027969 Exosome Malignant melanoma cell Microarray 23056502
RLID00027970 Exosome Brain tissue Microarray 23382797
RLID00027971 Exosome Plasma Next-generation sequencing 23663360
RLID00027972 Exosome Esophageal cancer cell Next-generation sequencing 25184951
RLID00027973 Microvesicle Plasma qRT-PCR 19002258
RLID00027974 Microvesicle Plasma Next-generation sequencing 23077538
RLID00027976 Microvesicle Follicular fluid Microarray 23666971
RLID00027977 Mitochondrion Skeletal muscular cell In situ hybridization|qRT-PCR 21637849
RLID00027978 Mitochondrion HeLa cell Next-generation sequencing 22984580
RLID00027979 Mitochondrion Eembryonic kidney cell Next-generation sequencing 22984580
RLID00027980 Nucleus Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00027981 Nucleus Colon adenocarcinoma cell Microarray 20864815
RLID00027982 Nucleus HeLa cell Next-generation sequencing 22058130
RLID00027983 Circulating Plasma Next-generation sequencing 25415674
RLID00027984 Exosome Urine Next-generation sequencing 25135963
RLID00027985 Nucleolus HeLa|MCF7 Microarray 24918059
RLID00027986 Exosome Saliva Next-generation sequencing 23302638
RLID00027987 Exosome Serum Next-generation sequencing 24683445
RLID00027988 Exosome Plasma Next-generation sequencing 24683445
RLID00027989 Circulating Plasma RT-PCR 24633190
RLID00027990 Cytoplasm HeLa|MCF7 Microarray 24918059
RLID00027991 Nucleus HeLa|MCF7 Microarray 24918059
RLID00027992 Mitochondrion Myoblast In situ hybridization|qRT-PCR 21637849
RLID00027993 Exosome Gastric cancer cell - 22529849
RLID00027994 Exosome Saliva - 22529849
RLID00027995 Exosome Renal carcinomas cell - 22529849
RLID00027996 Circulating Serum Next-generation sequencing 22719975
RLID00027997 Exosome Mast cell Microarray 24009880