Detail
| RLID: | RLID00027998 |
| RNA Symbol: | hsa-let-7c-5p |
| RNA Category: | miRNA |
| Organism: | Homo sapiens |
| Subcellular Localization: | |
| Localization | Tissue | Validated Method | PMID |
| Circulating | Serum | qRT-PCR | 21098710 |
| Description: By selecting miRNAs that have 3-fold higher expression in HBV compared with control serum, we identified total of 13 upregulated miRNAs, including miR-375, miR-92a, miR-10a, miR-223, miR-423, miR-23b/a, miR-342-3p, miR-99a, miR-122a, miR-125b, miR-150, and let-7c. As shown in Figure 2, the upregulation of these 13 miRNA expressions in the serum of HBV cases, compared with those of controls, was largely consistent when detected by Solexa in pooled samples and qRT-PCR in individual samples. Data are collected from Figure 2. | |||
Other Subcellular Localization:
| RLID | Localization | Tissue | Validated Method | PMID |
| RLID00027999 | Circulating | Blood | qRT-PCR|Microarray | 23424776 |
| RLID00028000 | Circulating | Cerebrospinal fluid | Next-generation sequencing|RT-PCR | 23525801 |
| RLID00028001 | Circulating | Serum | Next-generation sequencing|RT-PCR | 23525801 |
| RLID00028002 | Circulating | Serum | Next-generation sequencing | 23641832 |
| RLID00028003 | Circulating | Serum | Next-generation sequencing | 25359176 |
| RLID00028004 | Cytoplasm | Nasopharyngeal carcinoma cell | Next-generation sequencing | 20498841 |
| RLID00028005 | Cytoplasm | HeLa cell | Microarray | 21695135 |
| RLID00028006 | Extracellular vesicle | HEK293T|HMEC-1|Mononuclear cell | Next-generation sequencing | 22849433 |
| RLID00028007 | Exosome | Serum | Microarray | 18589210 |
| RLID00028008 | Exosome | Saliva | Microarray | 19627513 |
| RLID00028009 | Exosome | Breast cancer cell | Microarray | 20976003 |
| RLID00028010 | Exosome | Dendritic cell | Microarray | 21505438 |
| RLID00028011 | Exosome | B cell | Microarray | 21505438 |
| RLID00028012 | Exosome | Breast milk | Next-generation sequencing | 22211110 |
| RLID00028013 | Exosome | Malignant melanoma cell | Microarray | 23056502 |
| RLID00028014 | Exosome | Brain tissue | Microarray | 23382797 |
| RLID00028015 | Exosome | Plasma | Next-generation sequencing | 23663360 |
| RLID00028016 | Exosome | Esophageal cancer cell | Next-generation sequencing | 25184951 |
| RLID00028017 | Microvesicle | Plasma | Next-generation sequencing | 23077538 |
| RLID00028018 | Microvesicle | Seminal Plasma | Microarray | 23539611 |
| RLID00028019 | Microvesicle | Follicular fluid | Microarray | 23666971 |
| RLID00028020 | Mitochondrion | Skeletal muscular cell | In situ hybridization|qRT-PCR | 21637849 |
| RLID00028021 | Mitochondrion | HeLa cell | Next-generation sequencing | 22984580 |
| RLID00028022 | Mitochondrion | Eembryonic kidney cell | Next-generation sequencing | 22984580 |
| RLID00028023 | Nucleus | Nasopharyngeal carcinoma cell | Next-generation sequencing | 20498841 |
| RLID00028024 | Nucleus | Colon adenocarcinoma cell | Microarray | 20864815 |
| RLID00028025 | Nucleus | HeLa cell | Next-generation sequencing | 22058130 |
| RLID00028026 | Mitochondrion | Myoblast | In situ hybridization|qRT-PCR | 21637849 |
| RLID00028027 | Exosome | Gastric cancer cell | - | 22529849 |
| RLID00028028 | Exosome | Renal carcinomas cell | - | 22529849 |
| RLID00028029 | Circulating | Serum | Next-generation sequencing | 22719975 |