Detail

RLID: RLID00028018
RNA Symbol: hsa-let-7c-5p
RNA Category: miRNA
Organism: Homo sapiens
Sequence:
Homology: aae-let-7 (Aedes aegypti), bta-let-7a-5p (Bos taurus)
Network:
Subcellular Localization:
Localization Tissue Validated Method PMID
Microvesicle Seminal Plasma Microarray 23539611
Description: MiRNAs shuttled by SMVs in seminal plasma are potent non-invasive biomarkers to evaluate defects originating from the different organs of the male reproductive tract, including the epididymis (Wang et al., 2011). In order to assess the reversibility of post-vasectomy miRNA sequelae, we investigated whether SMV miRNAs altered by vasectomy could be retrieved in SMVs from normospermic vasovasostomized donors. miRNA microarray profiling performed on SMVs from normal, vasectomized and vasovasostomized donors identified 313 miRNAs whose intensity was above the threshold of detection. Among these miRNAs, 293 were detected in samples from normal donors, 275 in vasectomized donors and 298 in vasovasostomized donors (Fig. 3, Supplementary data, Table SIV). Data are collected from Table S4.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00027998 Circulating Serum qRT-PCR 21098710
RLID00027999 Circulating Blood qRT-PCR|Microarray 23424776
RLID00028000 Circulating Cerebrospinal fluid Next-generation sequencing|RT-PCR 23525801
RLID00028001 Circulating Serum Next-generation sequencing|RT-PCR 23525801
RLID00028002 Circulating Serum Next-generation sequencing 23641832
RLID00028003 Circulating Serum Next-generation sequencing 25359176
RLID00028004 Cytoplasm Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00028005 Cytoplasm HeLa cell Microarray 21695135
RLID00028006 Extracellular vesicle HEK293T|HMEC-1|Mononuclear cell Next-generation sequencing 22849433
RLID00028007 Exosome Serum Microarray 18589210
RLID00028008 Exosome Saliva Microarray 19627513
RLID00028009 Exosome Breast cancer cell Microarray 20976003
RLID00028010 Exosome Dendritic cell Microarray 21505438
RLID00028011 Exosome B cell Microarray 21505438
RLID00028012 Exosome Breast milk Next-generation sequencing 22211110
RLID00028013 Exosome Malignant melanoma cell Microarray 23056502
RLID00028014 Exosome Brain tissue Microarray 23382797
RLID00028015 Exosome Plasma Next-generation sequencing 23663360
RLID00028016 Exosome Esophageal cancer cell Next-generation sequencing 25184951
RLID00028017 Microvesicle Plasma Next-generation sequencing 23077538
RLID00028019 Microvesicle Follicular fluid Microarray 23666971
RLID00028020 Mitochondrion Skeletal muscular cell In situ hybridization|qRT-PCR 21637849
RLID00028021 Mitochondrion HeLa cell Next-generation sequencing 22984580
RLID00028022 Mitochondrion Eembryonic kidney cell Next-generation sequencing 22984580
RLID00028023 Nucleus Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00028024 Nucleus Colon adenocarcinoma cell Microarray 20864815
RLID00028025 Nucleus HeLa cell Next-generation sequencing 22058130
RLID00028026 Mitochondrion Myoblast In situ hybridization|qRT-PCR 21637849
RLID00028027 Exosome Gastric cancer cell - 22529849
RLID00028028 Exosome Renal carcinomas cell - 22529849
RLID00028029 Circulating Serum Next-generation sequencing 22719975