Detail

RLID: RLID00028110
RNA Symbol: hsa-let-7f-5p
RNA Category: miRNA
Organism: Homo sapiens
Aliase: hsa-let-7f
Sequence:
Homology: aae-let-7 (Aedes aegypti), bta-let-7a-5p (Bos taurus)
Network:
Subcellular Localization:
Localization Tissue Validated Method PMID
Exosome Breast cancer cell Microarray 24468161
Description: Figure 3: Differential gene expression in exosome-like vesicles. A) Hierarchical clustering was used to display miRNAs differentially expressed in each vesicle type. The extent of green (decreased fold change) or red (increased fold change) colors is directly proportional to the magnitude of differential expression of miRNAs. To perform these comparisons, probe sets whose target was not detected in any sample were eliminated from the data matrix. The data were grouped by type of exosome-like vesicles and members of each group were pooled, before a Student's t-test was used to identify those miRNAs that were expressed in a statistically significant manner (P < 0.05). B) miRNA profiles of the MDA-Exo versus MCF-Exo. Bars represent fold change of hybridization signals in MDA-Exo against MCF-Exo. Blue and red bars display relatively higher miRNA expressions in MDA-Exo and MCF-Exo, respectively. The miRNAs were quantified using the universal reference in equimolar concentrations and cross referenced with experimental data. Then the expression values were compared in two types of exosome-like vesicles (three independent experiments; P < 0.05). Data are collected from Figure 3.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00028099 Circulating Cerebrospinal fluid Next-generation sequencing|RT-PCR 23525801
RLID00028100 Circulating Serum Next-generation sequencing|RT-PCR 23525801
RLID00028101 Circulating Serum Next-generation sequencing 23641832
RLID00028102 Circulating Plasma qRT-PCR 24937531
RLID00028103 Cytoplasm Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00028104 Exosome Serum Microarray 18589210
RLID00028105 Exosome Breast cancer cell Microarray 20976003
RLID00028106 Exosome Dendritic cell Microarray 21505438
RLID00028107 Exosome B cell Microarray 21505438
RLID00028108 Exosome Brain tissue Microarray 23382797
RLID00028109 Exosome Plasma Next-generation sequencing 23663360
RLID00028111 Exosome Esophageal cancer cell Next-generation sequencing 25184951
RLID00028112 Microvesicle Plasma Next-generation sequencing 23077538
RLID00028113 Microvesicle Seminal Plasma Microarray 23539611
RLID00028114 Microvesicle Hepatoma cell qRT-PCR|Microarray 23771658
RLID00028115 Mitochondrion HeLa cell Next-generation sequencing 22984580
RLID00028116 Mitochondrion Eembryonic kidney cell Next-generation sequencing 22984580
RLID00028117 Nucleus Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00028118 Nucleus Colon adenocarcinoma cell Microarray 20864815
RLID00028119 Nucleus HeLa cell Next-generation sequencing 22058130
RLID00028120 Circulating Plasma Next-generation sequencing 25415674
RLID00028121 Nucleolus HeLa|MCF7 Microarray 24918059
RLID00028122 Exosome Serum Next-generation sequencing 24683445
RLID00028123 Exosome Plasma Next-generation sequencing 24683445
RLID00028124 Cytoplasm HeLa|MCF7 Microarray 24918059
RLID00028125 Nucleus HeLa|MCF7 Microarray 24918059
RLID00028126 Mitochondrion Myoblast In situ hybridization|qRT-PCR 21637849
RLID00028127 Exosome Gastric cancer cell - 22529849
RLID00028128 Exosome Renal carcinomas cell - 22529849
RLID00028129 Circulating Serum Next-generation sequencing 22719975
RLID00028130 Circulating Plasma Microarray 22997154