Detail

RLID: RLID00028120
RNA Symbol: hsa-let-7f-5p
RNA Category: miRNA
Organism: Homo sapiens
Aliase: hsa-let-7f
Sequence:
Homology: aae-let-7 (Aedes aegypti), bta-let-7a-5p (Bos taurus)
Network:
Subcellular Localization:
Localization Tissue Validated Method PMID
Circulating Plasma Next-generation sequencing 25415674
Description: To determine the effects of CAD on the levels of circulating miRNAs, we performed miRNA profile analysis by deep sequencing using RNA isolated from 20 patients with CAD and 20 healthy controls. Two hundred ninety-six miRNAs were detected in the plasma of healthy individuals and 196 in patients with CAD. Among all the miRNAs detected, 173 miRNAs were found in both groups, only 123 miRNAs were detected in healthy individuals, while only 23 miRNAs were detected in patients with CAD. The levels of circulating miRNA profoundly differed between patients and healthy controls, as demonstrated in the scatter (Figure ?(Figure1).1). There were 53 miRNAs that showed more than 2-fold differential expression between groups. Detailed information of these miRNAs is listed in supplementary Table 2.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00028099 Circulating Cerebrospinal fluid Next-generation sequencing|RT-PCR 23525801
RLID00028100 Circulating Serum Next-generation sequencing|RT-PCR 23525801
RLID00028101 Circulating Serum Next-generation sequencing 23641832
RLID00028102 Circulating Plasma qRT-PCR 24937531
RLID00028103 Cytoplasm Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00028104 Exosome Serum Microarray 18589210
RLID00028105 Exosome Breast cancer cell Microarray 20976003
RLID00028106 Exosome Dendritic cell Microarray 21505438
RLID00028107 Exosome B cell Microarray 21505438
RLID00028108 Exosome Brain tissue Microarray 23382797
RLID00028109 Exosome Plasma Next-generation sequencing 23663360
RLID00028110 Exosome Breast cancer cell Microarray 24468161
RLID00028111 Exosome Esophageal cancer cell Next-generation sequencing 25184951
RLID00028112 Microvesicle Plasma Next-generation sequencing 23077538
RLID00028113 Microvesicle Seminal Plasma Microarray 23539611
RLID00028114 Microvesicle Hepatoma cell qRT-PCR|Microarray 23771658
RLID00028115 Mitochondrion HeLa cell Next-generation sequencing 22984580
RLID00028116 Mitochondrion Eembryonic kidney cell Next-generation sequencing 22984580
RLID00028117 Nucleus Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00028118 Nucleus Colon adenocarcinoma cell Microarray 20864815
RLID00028119 Nucleus HeLa cell Next-generation sequencing 22058130
RLID00028121 Nucleolus HeLa|MCF7 Microarray 24918059
RLID00028122 Exosome Serum Next-generation sequencing 24683445
RLID00028123 Exosome Plasma Next-generation sequencing 24683445
RLID00028124 Cytoplasm HeLa|MCF7 Microarray 24918059
RLID00028125 Nucleus HeLa|MCF7 Microarray 24918059
RLID00028126 Mitochondrion Myoblast In situ hybridization|qRT-PCR 21637849
RLID00028127 Exosome Gastric cancer cell - 22529849
RLID00028128 Exosome Renal carcinomas cell - 22529849
RLID00028129 Circulating Serum Next-generation sequencing 22719975
RLID00028130 Circulating Plasma Microarray 22997154