Detail

RLID: RLID00028142
RNA Symbol: hsa-miR-15a-5p
RNA Category: miRNA
Organism: Homo sapiens
Aliase: hsa-miR-15a
Sequence:
Homology: bta-miR-15b (Bos taurus), bta-miR-16a (Bos taurus)
Network:
Subcellular Localization:
Localization Tissue Validated Method PMID
Microvesicle Seminal Plasma Microarray 23539611
Description: MiRNAs shuttled by SMVs in seminal plasma are potent non-invasive biomarkers to evaluate defects originating from the different organs of the male reproductive tract, including the epididymis (Wang et al., 2011). In order to assess the reversibility of post-vasectomy miRNA sequelae, we investigated whether SMV miRNAs altered by vasectomy could be retrieved in SMVs from normospermic vasovasostomized donors. miRNA microarray profiling performed on SMVs from normal, vasectomized and vasovasostomized donors identified 313 miRNAs whose intensity was above the threshold of detection. Among these miRNAs, 293 were detected in samples from normal donors, 275 in vasectomized donors and 298 in vasovasostomized donors (Fig. 3, Supplementary data, Table SIV). Data are collected from Table S4.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00028131 Circulating Cerebrospinal fluid Next-generation sequencing|RT-PCR 23525801
RLID00028132 Circulating Serum Next-generation sequencing|RT-PCR 23525801
RLID00028133 Cytoplasm Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00028134 Exosome Dendritic cell Microarray 21505438
RLID00028135 Exosome B cell Microarray 21505438
RLID00028136 Exosome Breast milk Next-generation sequencing 22211110
RLID00028137 Exosome Brain tissue Microarray 23382797
RLID00028138 Exosome Plasma Next-generation sequencing 23663360
RLID00028139 Exosome Serum Next-generation sequencing 25349172
RLID00028140 Microvesicle Plasma qRT-PCR 19002258
RLID00028141 Microvesicle Plasma Next-generation sequencing 23077538
RLID00028143 Microvesicle Hepatoma cell qRT-PCR|Microarray 23771658
RLID00028144 Mitochondrion Skeletal muscular cell In situ hybridization|qRT-PCR 21637849
RLID00028145 Mitochondrion HeLa cell Next-generation sequencing 22984580
RLID00028146 Mitochondrion Eembryonic kidney cell Next-generation sequencing 22984580
RLID00028147 Nucleus Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00028148 Nucleus Colon adenocarcinoma cell Microarray 20864815
RLID00028149 Nucleus HeLa cell Next-generation sequencing 22058130
RLID00028150 Nucleolus HeLa|MCF7 Microarray 24918059
RLID00028151 Exosome Serum Next-generation sequencing 24683445
RLID00028152 Exosome Plasma Next-generation sequencing 24683445
RLID00028153 Cytoplasm HeLa|MCF7 Microarray 24918059
RLID00028154 Nucleus HeLa|MCF7 Microarray 24918059
RLID00028155 Exosome Renal carcinomas cell - 22529849
RLID00028156 Circulating Serum Next-generation sequencing 22719975
RLID00028157 Exosome Mast cell Microarray 24009880
RLID00028158 Circulating Plasma RT-PCR 24130905