Detail

RLID: RLID00028173
RNA Symbol: hsa-miR-16-5p
RNA Category: miRNA
Organism: Homo sapiens
Aliase: hsa-miR-16
Sequence:
Homology: bta-miR-15b (Bos taurus), bta-miR-16a (Bos taurus)
Network:
Subcellular Localization:
Localization Tissue Validated Method PMID
Exosome Breast cancer cell Microarray 24468161
Description: Figure 3: Differential gene expression in exosome-like vesicles. A) Hierarchical clustering was used to display miRNAs differentially expressed in each vesicle type. The extent of green (decreased fold change) or red (increased fold change) colors is directly proportional to the magnitude of differential expression of miRNAs. To perform these comparisons, probe sets whose target was not detected in any sample were eliminated from the data matrix. The data were grouped by type of exosome-like vesicles and members of each group were pooled, before a Student's t-test was used to identify those miRNAs that were expressed in a statistically significant manner (P < 0.05). B) miRNA profiles of the MDA-Exo versus MCF-Exo. Bars represent fold change of hybridization signals in MDA-Exo against MCF-Exo. Blue and red bars display relatively higher miRNA expressions in MDA-Exo and MCF-Exo, respectively. The miRNAs were quantified using the universal reference in equimolar concentrations and cross referenced with experimental data. Then the expression values were compared in two types of exosome-like vesicles (three independent experiments; P < 0.05). Data are collected from Figure 3.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00028159 Circulating Serum Microarray 19597549
RLID00028160 Circulating Plasma qRT-PCR|Microarray 20883153
RLID00028161 Circulating Plasma qRT-PCR 22262318
RLID00028162 Circulating Cerebrospinal fluid Next-generation sequencing|RT-PCR 23525801
RLID00028163 Circulating Serum Next-generation sequencing|RT-PCR 23525801
RLID00028164 Circulating Serum Next-generation sequencing 23641832
RLID00028165 Circulating Follicular fluid Microarray 23666971
RLID00028166 Cytoplasm Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00028167 Cytoplasm HeLa cell Microarray 21695135
RLID00028168 Exosome Serum Microarray 18589210
RLID00028169 Exosome Dendritic cell Microarray 21505438
RLID00028170 Exosome B cell Microarray 21505438
RLID00028171 Exosome Brain tissue Microarray 23382797
RLID00028172 Exosome Plasma Next-generation sequencing 23663360
RLID00028174 Microvesicle Plasma qRT-PCR 19002258
RLID00028175 Microvesicle Glioblastoma cell qRT-PCR|Microarray 19011622
RLID00028176 Microvesicle Plasma Next-generation sequencing 23077538
RLID00028177 Microvesicle Seminal Plasma Microarray 23539611
RLID00028178 Microvesicle Hepatoma cell qRT-PCR|Microarray 23771658
RLID00028179 Mitochondrion HeLa cell Next-generation sequencing 22984580
RLID00028180 Mitochondrion Eembryonic kidney cell Next-generation sequencing 22984580
RLID00028181 Nucleus Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00028182 Nucleus Neural progenitor cell qRT-PCR|Microarray 21363885
RLID00028183 Nucleolus HeLa|MCF7 Microarray 24918059
RLID00028184 Exosome Serum Next-generation sequencing 24683445
RLID00028185 Exosome Plasma Next-generation sequencing 24683445
RLID00028186 Cytoplasm HeLa|MCF7 Microarray 24918059
RLID00028187 Nucleus HeLa|MCF7 Microarray 24918059
RLID00028188 Circulating Plasma RT-PCR 24633190
RLID00028189 Microvesicle A549|HepG2 Microarrays|RT-PCR 20615901
RLID00028190 Exosome A549|HepG2 Microarrays|RT-PCR 20615901
RLID00028191 Exosome Epithelial cell - 22529849
RLID00028192 Exosome Liver carcinoma cell - 22529849
RLID00028193 Exosome Kidney cell - 22529849
RLID00028194 Exosome Glioblastoma cell - 22529849
RLID00028195 Circulating Serum Next-generation sequencing 22719975
RLID00028196 Circulating Plasma RT-PCR 24130905