Detail
| RLID: | RLID00028197 |
| RNA Symbol: | hsa-miR-17-5p |
| RNA Category: | miRNA |
| Organism: | Homo sapiens |
| Aliase: | hsa-miR-17-5p, hsa-miR-17 |
| Subcellular Localization: | |
| Localization | Tissue | Validated Method | PMID |
| Circulating | serum | qRT-PCR|RNA-seq | 22094284 |
| Description: When compared with family schizophrenia patients, circulating miR-219-2-3p, miR-92a, miR-346, let-7g and miR-17 were significantly higher in sporadic schizophrenia ( p < 0.001, Fig. 4 ). On contrary, miR-181b and miR-195 were significantlydown-regulated in sporadic schizophrenia compared with family schizophrenia patients ( p < 0.001), miR-1308 was slightly lower in sporadic schizophrenia compared family schizophrenia patients (0.05 < p < 0.001), and miR-103 was highly consistent between sporadic schizophrenia and family schizophrenia patients ( p > 0.05). These data indicate that there is a close relationship between levels of circulating miRNAs and schizophrenia patients whether they have the family history or not. | |||
Other Subcellular Localization:
| RLID | Localization | Tissue | Validated Method | PMID |
| RLID00028198 | Circulating | Plasma | qRT-PCR | 22262318 |
| RLID00028199 | Circulating | Serum | qRT-PCR | 23056289 |
| RLID00028200 | Circulating | Follicular fluid | Microarray | 23666971 |
| RLID00028201 | Circulating | Plasma | - | 24456939 |
| RLID00028202 | Cytoplasm | Nasopharyngeal carcinoma cell | Next-generation sequencing | 20498841 |
| RLID00028203 | Cytoplasm | Neural progenitor cell | qRT-PCR|Microarray | 21363885 |
| RLID00028204 | Cytoplasm | HeLa cell | Microarray | 21695135 |
| RLID00028205 | Extracellular vesicle | HEK293T|HMEC-1|Mononuclear cell | Next-generation sequencing | 22849433 |
| RLID00028206 | Exosome | Serum | Microarray | 18589210 |
| RLID00028207 | Exosome | Saliva | Microarray | 19627513 |
| RLID00028208 | Exosome | Dendritic cell | Microarray | 21505438 |
| RLID00028209 | Exosome | B cell | Microarray | 21505438 |
| RLID00028210 | Exosome | Malignant melanoma cell | Microarray | 23056502 |
| RLID00028211 | Exosome | Brain tissue | Microarray | 23382797 |
| RLID00028212 | Exosome | Plasma | Next-generation sequencing | 23663360 |
| RLID00028213 | Microvesicle | Plasma | qRT-PCR | 19002258 |
| RLID00028214 | Microvesicle | Seminal Plasma | Microarray | 23539611 |
| RLID00028215 | Microvesicle | Follicular fluid | Microarray | 23666971 |
| RLID00028216 | Mitochondrion | Skeletal muscular cell | In situ hybridization|qRT-PCR | 21637849 |
| RLID00028217 | Mitochondrion | HeLa cell | Next-generation sequencing | 22984580 |
| RLID00028218 | Mitochondrion | Eembryonic kidney cell | Next-generation sequencing | 22984580 |
| RLID00028219 | Nucleus | Nasopharyngeal carcinoma cell | Next-generation sequencing | 20498841 |
| RLID00028220 | Nucleus | Colon adenocarcinoma cell | Microarray | 20864815 |
| RLID00028221 | Nucleus | HeLa cell | Next-generation sequencing | 22058130 |
| RLID00028222 | Circulating | Plasma | Next-generation sequencing | 25415674 |
| RLID00028223 | Nucleolus | HeLa|MCF7 | Microarray | 24918059 |
| RLID00028224 | Exosome | Saliva | Next-generation sequencing | 23302638 |
| RLID00028225 | Exosome | Cerebrospinal fluid | Next-generation sequencing | 25420022 |
| RLID00028226 | Exosome | Serum | Next-generation sequencing | 24683445 |
| RLID00028227 | Exosome | Plasma | Next-generation sequencing | 24683445 |
| RLID00028228 | Cytoplasm | HeLa|MCF7 | Microarray | 24918059 |
| RLID00028229 | Nucleus | HeLa|MCF7 | Microarray | 24918059 |
| RLID00028230 | Exosome | Saliva | - | 22529849 |
| RLID00028231 | Exosome | PBMC | - | 22529849 |
| RLID00028232 | Circulating | Serum | Next-generation sequencing | 22719975 |