Detail

RLID: RLID00028260
RNA Symbol: hsa-miR-18a-5p
RNA Category: miRNA
Organism: Homo sapiens
Aliase: hsa-miR-18, hsa-miR-18a
Sequence:
Homology: bta-miR-106b (Bos taurus), bta-miR-17-3p (Bos taurus)
Network:
Subcellular Localization:
Localization Tissue Validated Method PMID
Microvesicle Seminal Plasma Microarray 23539611
Description: MiRNAs shuttled by SMVs in seminal plasma are potent non-invasive biomarkers to evaluate defects originating from the different organs of the male reproductive tract, including the epididymis (Wang et al., 2011). In order to assess the reversibility of post-vasectomy miRNA sequelae, we investigated whether SMV miRNAs altered by vasectomy could be retrieved in SMVs from normospermic vasovasostomized donors. miRNA microarray profiling performed on SMVs from normal, vasectomized and vasovasostomized donors identified 313 miRNAs whose intensity was above the threshold of detection. Among these miRNAs, 293 were detected in samples from normal donors, 275 in vasectomized donors and 298 in vasovasostomized donors (Fig. 3, Supplementary data, Table SIV). Data are collected from Table S4.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00028249 Cytoplasm Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00028250 Cytoplasm Neural progenitor cell qRT-PCR|Microarray 21363885
RLID00028251 Cytoplasm HeLa cell Microarray 21695135
RLID00028252 Extracellular vesicle HEK293T|HMEC-1|Mononuclear cell Next-generation sequencing 22849433
RLID00028253 Exosome Serum Microarray 18589210
RLID00028254 Exosome Dendritic cell Microarray 21505438
RLID00028255 Exosome B cell Microarray 21505438
RLID00028256 Exosome Breast milk Next-generation sequencing 22211110
RLID00028257 Exosome Malignant melanoma cell Microarray 23056502
RLID00028258 Exosome Brain tissue Microarray 23382797
RLID00028259 Exosome Plasma Next-generation sequencing 23663360
RLID00028261 Mitochondrion Skeletal muscular cell In situ hybridization|qRT-PCR 21637849
RLID00028262 Mitochondrion Eembryonic kidney cell Next-generation sequencing 22984580
RLID00028263 Nucleus Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00028264 Nucleus HeLa cell Next-generation sequencing 22058130
RLID00028265 Exosome Cerebrospinal fluid Next-generation sequencing 25420022
RLID00028266 Circulating Plasma Next-generation sequencing 25415674
RLID00028267 Nucleolus HeLa|MCF7 Microarray 24918059
RLID00028268 Exosome Serum Next-generation sequencing 24683445
RLID00028269 Exosome Plasma Next-generation sequencing 24683445
RLID00028270 Cytoplasm HeLa|MCF7 Microarray 24918059
RLID00028271 Nucleus HeLa|MCF7 Microarray 24918059
RLID00028272 Exosome Ovarian tumor cell - 22529849