Detail

RLID: RLID00028266
RNA Symbol: hsa-miR-18a-5p
RNA Category: miRNA
Organism: Homo sapiens
Aliase: hsa-miR-18, hsa-miR-18a
Sequence:
Homology: bta-miR-106b (Bos taurus), bta-miR-17-3p (Bos taurus)
Network:
Subcellular Localization:
Localization Tissue Validated Method PMID
Circulating Plasma Next-generation sequencing 25415674
Description: To determine the effects of CAD on the levels of circulating miRNAs, we performed miRNA profile analysis by deep sequencing using RNA isolated from 20 patients with CAD and 20 healthy controls. Two hundred ninety-six miRNAs were detected in the plasma of healthy individuals and 196 in patients with CAD. Among all the miRNAs detected, 173 miRNAs were found in both groups, only 123 miRNAs were detected in healthy individuals, while only 23 miRNAs were detected in patients with CAD. The levels of circulating miRNA profoundly differed between patients and healthy controls, as demonstrated in the scatter (Figure ?(Figure1).1). There were 53 miRNAs that showed more than 2-fold differential expression between groups. Detailed information of these miRNAs is listed in supplementary Table 2.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00028249 Cytoplasm Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00028250 Cytoplasm Neural progenitor cell qRT-PCR|Microarray 21363885
RLID00028251 Cytoplasm HeLa cell Microarray 21695135
RLID00028252 Extracellular vesicle HEK293T|HMEC-1|Mononuclear cell Next-generation sequencing 22849433
RLID00028253 Exosome Serum Microarray 18589210
RLID00028254 Exosome Dendritic cell Microarray 21505438
RLID00028255 Exosome B cell Microarray 21505438
RLID00028256 Exosome Breast milk Next-generation sequencing 22211110
RLID00028257 Exosome Malignant melanoma cell Microarray 23056502
RLID00028258 Exosome Brain tissue Microarray 23382797
RLID00028259 Exosome Plasma Next-generation sequencing 23663360
RLID00028260 Microvesicle Seminal Plasma Microarray 23539611
RLID00028261 Mitochondrion Skeletal muscular cell In situ hybridization|qRT-PCR 21637849
RLID00028262 Mitochondrion Eembryonic kidney cell Next-generation sequencing 22984580
RLID00028263 Nucleus Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00028264 Nucleus HeLa cell Next-generation sequencing 22058130
RLID00028265 Exosome Cerebrospinal fluid Next-generation sequencing 25420022
RLID00028267 Nucleolus HeLa|MCF7 Microarray 24918059
RLID00028268 Exosome Serum Next-generation sequencing 24683445
RLID00028269 Exosome Plasma Next-generation sequencing 24683445
RLID00028270 Cytoplasm HeLa|MCF7 Microarray 24918059
RLID00028271 Nucleus HeLa|MCF7 Microarray 24918059
RLID00028272 Exosome Ovarian tumor cell - 22529849