Detail

RLID: RLID00028441
RNA Symbol: hsa-miR-22-3p
RNA Category: miRNA
Organism: Homo sapiens
Aliase: hsa-miR-22
Sequence:
Homology: eca-miR-22 (Equus caballus), hsa-miR-22-5p (Homo sapiens)
Network:
Subcellular Localization:
Localization Tissue Validated Method PMID
Circulating Plasma Next-generation sequencing 25415674
Description: To determine the effects of CAD on the levels of circulating miRNAs, we performed miRNA profile analysis by deep sequencing using RNA isolated from 20 patients with CAD and 20 healthy controls. Two hundred ninety-six miRNAs were detected in the plasma of healthy individuals and 196 in patients with CAD. Among all the miRNAs detected, 173 miRNAs were found in both groups, only 123 miRNAs were detected in healthy individuals, while only 23 miRNAs were detected in patients with CAD. The levels of circulating miRNA profoundly differed between patients and healthy controls, as demonstrated in the scatter (Figure ?(Figure1).1). There were 53 miRNAs that showed more than 2-fold differential expression between groups. Detailed information of these miRNAs is listed in supplementary Table 2.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00028420 Circulating Cerebrospinal fluid Next-generation sequencing|RT-PCR 23525801
RLID00028421 Circulating Serum Next-generation sequencing|RT-PCR 23525801
RLID00028422 Circulating Serum Next-generation sequencing 23641832
RLID00028423 Circulating Serum Next-generation sequencing 25359176
RLID00028424 Cytoplasm Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00028425 Extracellular vesicle HEK293T|HMEC-1|Mononuclear cell Next-generation sequencing 22849433
RLID00028426 Exosome Serum Microarray 18589210
RLID00028427 Exosome Dendritic cell Microarray 21505438
RLID00028428 Exosome B cell Microarray 21505438
RLID00028429 Exosome Malignant melanoma cell Microarray 23056502
RLID00028430 Exosome Brain tissue Microarray 23382797
RLID00028431 Exosome Plasma Next-generation sequencing 23663360
RLID00028432 Microvesicle Plasma Next-generation sequencing 23077538
RLID00028433 Microvesicle Seminal Plasma Microarray 23539611
RLID00028434 Microvesicle Hepatoma cell qRT-PCR|Microarray 23771658
RLID00028435 Mitochondrion Skeletal muscular cell In situ hybridization|qRT-PCR 21637849
RLID00028436 Mitochondrion HeLa cell Next-generation sequencing 22984580
RLID00028437 Mitochondrion Eembryonic kidney cell Next-generation sequencing 22984580
RLID00028438 Nucleus Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00028439 Nucleus HeLa cell Next-generation sequencing 22058130
RLID00028440 Exosome Cerebrospinal fluid Next-generation sequencing 25420022
RLID00028442 Nucleolus HeLa|MCF7 Microarray 24918059
RLID00028443 Exosome Serum Next-generation sequencing 24683445
RLID00028444 Exosome Plasma Next-generation sequencing 24683445
RLID00028445 Nucleus HeLa|MCF7 Microarray 24918059
RLID00028446 Microvesicle A549|HepG2 Microarrays|RT-PCR 20615901
RLID00028447 Exosome A549|HepG2 Microarrays|RT-PCR 20615901
RLID00028448 Exosome Ovarian - 22529849
RLID00028449 Exosome Renal carcinomas cell - 22529849
RLID00028450 Exosome Epithelial cell - 22529849
RLID00028451 Exosome Liver carcinoma cell - 22529849
RLID00028452 Circulating Serum Next-generation sequencing 22719975
RLID00028453 Exosome Mast cell Microarray 24009880