Detail

RLID: RLID00029424
RNA Symbol: hsa-miR-199a-5p
RNA Category: miRNA
Organism: Homo sapiens
Aliase: hsa-miR-199a
Sequence:
Homology: hsa-miR-199a-3p (Homo sapiens), hsa-miR-199b-3p (Homo sapiens)
Network:
Subcellular Localization:
Localization Tissue Validated Method PMID
Circulating Plasma Next-generation sequencing 25415674
Description: To determine the effects of CAD on the levels of circulating miRNAs, we performed miRNA profile analysis by deep sequencing using RNA isolated from 20 patients with CAD and 20 healthy controls. Two hundred ninety-six miRNAs were detected in the plasma of healthy individuals and 196 in patients with CAD. Among all the miRNAs detected, 173 miRNAs were found in both groups, only 123 miRNAs were detected in healthy individuals, while only 23 miRNAs were detected in patients with CAD. The levels of circulating miRNA profoundly differed between patients and healthy controls, as demonstrated in the scatter (Figure ?(Figure1).1). There were 53 miRNAs that showed more than 2-fold differential expression between groups. Detailed information of these miRNAs is listed in supplementary Table 2.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00029418 Circulating Serum Next-generation sequencing|RT-PCR 23525801
RLID00029419 Cytoplasm Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00029420 Exosome Brain tissue Microarray 23382797
RLID00029421 Exosome Plasma Next-generation sequencing 23663360
RLID00029422 Mitochondrion Skeletal muscular cell In situ hybridization|qRT-PCR 21637849
RLID00029423 Nucleus Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00029425 Exosome B cell Next-generation sequencing 25242326
RLID00029426 Circulating Serum qRT-PCR 25238238
RLID00029427 Exosome Serum Next-generation sequencing 24683445
RLID00029428 Exosome Plasma Next-generation sequencing 24683445