Detail
| RLID: | RLID00029654 |
| RNA Symbol: | hsa-miR-34a-5p |
| RNA Category: | miRNA |
| Organism: | Homo sapiens |
| Aliase: | hsa-miR-34a |
| Subcellular Localization: | |
| Localization | Tissue | Validated Method | PMID |
| Nucleus | HeLa cell | Next-generation sequencing | 22058130 |
| Description: Here, we present a data set excluding these RNA before sequencing through locked nucleic acids (LNA), greatly increasing pre-miRNA sequence counts with no discernable effect on pre-miRNA or mature miRNA sequencing. Analysis of profiles generated in total, nuclear and cytoplasmic cell fractions reveals that pre-miRNAs are subject to a wide range of regulatory processes involving loci-specific 3'- and 5'-end variation entailing complex cleavage patterns with co-occurring polyuridylation. Data were collected from Supplementary file. | |||
Other Subcellular Localization:
| RLID | Localization | Tissue | Validated Method | PMID |
| RLID00029639 | Circulating | Blood | qRT-PCR | 21398193 |
| RLID00029640 | Circulating | Cerebrospinal fluid | Next-generation sequencing|RT-PCR | 23525801 |
| RLID00029641 | Circulating | Serum | - | 24456939 |
| RLID00029642 | Cytoplasm | Neural progenitor cell | qRT-PCR|Microarray | 21363885 |
| RLID00029643 | Exosome | Serum | Microarray | 18589210 |
| RLID00029644 | Exosome | Dendritic cell | Microarray | 21505438 |
| RLID00029645 | Exosome | Breast milk | Next-generation sequencing | 22211110 |
| RLID00029646 | Exosome | Malignant melanoma cell | Microarray | 23056502 |
| RLID00029647 | Exosome | Brain tissue | Microarray | 23382797 |
| RLID00029648 | Exosome | Plasma | Next-generation sequencing | 23663360 |
| RLID00029649 | Exosome | Breast cancer cell | Microarray | 24468161 |
| RLID00029650 | Microvesicle | Seminal Plasma | Microarray | 23539611 |
| RLID00029651 | Mitochondrion | Skeletal muscular cell | In situ hybridization|qRT-PCR | 21637849 |
| RLID00029652 | Mitochondrion | HeLa cell | Next-generation sequencing | 22984580 |
| RLID00029653 | Mitochondrion | Eembryonic kidney cell | Next-generation sequencing | 22984580 |
| RLID00029655 | Exosome | Serum | Next-generation sequencing | 24683445 |
| RLID00029656 | Exosome | Plasma | Next-generation sequencing | 24683445 |
| RLID00029657 | Cytoplasm | HeLa|MCF7 | Microarray | 24918059 |
| RLID00029658 | Nucleus | HeLa|MCF7 | Microarray | 24918059 |
| RLID00029659 | Circulating | Plasma | qRT-PCR|Next-generation sequcencing | 24865854 |
| RLID00029660 | Microvesicle | Serum | RNA-seq|miRDeep3 | 24797360 |
| RLID00029661 | Exosome | Mast cell | Microarray | 24009880 |