Detail
| RLID: | RLID00029975 |
| RNA Symbol: | hsa-miR-221-3p |
| RNA Category: | miRNA |
| Organism: | Homo sapiens |
| Aliase: | hsa-miR-221 |
| Subcellular Localization: | |
| Localization | Tissue | Validated Method | PMID |
| Nucleus | HeLa cell | Next-generation sequencing | 22058130 |
| Description: Here, we present a data set excluding these RNA before sequencing through locked nucleic acids (LNA), greatly increasing pre-miRNA sequence counts with no discernable effect on pre-miRNA or mature miRNA sequencing. Analysis of profiles generated in total, nuclear and cytoplasmic cell fractions reveals that pre-miRNAs are subject to a wide range of regulatory processes involving loci-specific 3'- and 5'-end variation entailing complex cleavage patterns with co-occurring polyuridylation. Data were collected from Supplementary file. | |||
Other Subcellular Localization:
| RLID | Localization | Tissue | Validated Method | PMID |
| RLID00029956 | Circulating | Cerebrospinal fluid | Next-generation sequencing|RT-PCR | 23525801 |
| RLID00029957 | Circulating | Serum | Next-generation sequencing|RT-PCR | 23525801 |
| RLID00029958 | Circulating | Serum | Next-generation sequencing | 23641832 |
| RLID00029959 | Cytoplasm | Nasopharyngeal carcinoma cell | Next-generation sequencing | 20498841 |
| RLID00029960 | Cytoplasm | Neural progenitor cell | qRT-PCR|Microarray | 21363885 |
| RLID00029961 | Cytoplasm | HeLa cell | Microarray | 21695135 |
| RLID00029962 | Extracellular vesicle | HEK293T|HMEC-1|Mononuclear cell | Next-generation sequencing | 22849433 |
| RLID00029963 | Exosome | Serum | Microarray | 18589210 |
| RLID00029964 | Exosome | Dendritic cell | Microarray | 21505438 |
| RLID00029965 | Exosome | Colon|Liver|Lung | qRT-PCR | 22895844 |
| RLID00029966 | Exosome | Malignant melanoma cell | Microarray | 23056502 |
| RLID00029967 | Exosome | Brain tissue | Microarray | 23382797 |
| RLID00029968 | Microvesicle | Plasma | Next-generation sequencing | 23077538 |
| RLID00029969 | Microvesicle | Seminal Plasma | Microarray | 23539611 |
| RLID00029970 | Microvesicle | Hepatoma cell | qRT-PCR|Microarray | 23771658 |
| RLID00029971 | Mitochondrion | Skeletal muscular cell | In situ hybridization|qRT-PCR | 21637849 |
| RLID00029972 | Mitochondrion | HeLa cell | Next-generation sequencing | 22984580 |
| RLID00029973 | Mitochondrion | Eembryonic kidney cell | Next-generation sequencing | 22984580 |
| RLID00029974 | Nucleus | Nasopharyngeal carcinoma cell | Next-generation sequencing | 20498841 |
| RLID00029976 | Nucleolus | HeLa|MCF7 | Microarray | 24918059 |
| RLID00029977 | Exosome | Colon Cancer Cell Line | qRT-PCR|RNA-seq | 25330373 |
| RLID00029978 | Exosome | Serum | Next-generation sequencing | 24683445 |
| RLID00029979 | Exosome | Plasma | Next-generation sequencing | 24683445 |
| RLID00029980 | Cytoplasm | HeLa|MCF7 | Microarray | 24918059 |
| RLID00029981 | Circulating | Serum | qRT-PCR | 18766170 |
| RLID00029982 | Circulating | Serum | Next-generation sequencing | 22719975 |
| RLID00029983 | Exosome | Mast cell | Microarray | 24009880 |