Detail

RLID: RLID00030337
RNA Symbol: hsa-miR-124-3p
RNA Category: miRNA
Organism: Homo sapiens
Aliase: hsa-miR-124a, hsa-miR-124
Sequence:
Homology: aae-miR-124 (Aedes aegypti), hsa-miR-124-5p (Homo sapiens)
Network:
Subcellular Localization:
Localization Tissue Validated Method PMID
Circulating Serum qRT-PCR 22798503
Description: Our stem-loop RT-MGB qPCR in plasma and tissue samples from healthy individuals and patients with colon cancer presented in Table IV show that out of the 15 selected miRNAs exhibiting preferential expression and which have been shown to be related to colon carcinogenesis; nine of them (miR-7, miR-17-3p, miR-20a, miR-21, miR-92a, miR-96, miR-183, miR196a and miR-214) exhibited increased expression in plasma (and also in tissues) of patients with CRC, and that later TNM carcinoma stages had a more increased expression than did adenomas. On the other hand, six of the selected miRNAs (miR-124, miR-127-5p, miR-138, miR-143, miR-146a and miR-222) were reduced in expression in plasma (and also in tissues) of patients with CRC, the reduction becoming more pronounced during progression from early to later TNM carcinoma stages.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00030338 Circulating Cerebrospinal fluid Next-generation sequencing|RT-PCR 23525801
RLID00030339 Exosome Plasma Next-generation sequencing 23663360
RLID00030340 Mitochondrion Eembryonic kidney cell Next-generation sequencing 22984580
RLID00030341 Circulating Plasma Next-generation sequencing 25415674
RLID00030342 Microvesicle Cerebrospinal fluid RNA-seq|miRDeep3 24797360
RLID00030343 Circulating Serum Next-generation sequencing 22719975