Detail
| Localization |
Tissue |
Validated Method |
PMID |
| Circulating |
serum |
qRT-PCR|RNA-seq |
22094284 |
|
Description: When compared with family schizophrenia patients, circulating miR-219-2-3p, miR-92a, miR-346, let-7g and miR-17 were significantly higher in sporadic schizophrenia ( p < 0.001, Fig. 4 ). On contrary, miR-181b and miR-195 were significantlydown-regulated in sporadic schizophrenia compared with family schizophrenia patients ( p < 0.001), miR-1308 was slightly lower in sporadic schizophrenia compared family schizophrenia patients (0.05 < p < 0.001), and miR-103 was highly consistent between sporadic schizophrenia and family schizophrenia patients ( p > 0.05). These data indicate that there is a close relationship between levels of circulating miRNAs and schizophrenia patients whether they have the family history or not.
|
Other Subcellular Localization: