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Description: Microarray assay results showed a total of 36 differentially-expressed miRNAs, among which 15 miRNAs were considered as aberrantly expressed with a more than 2-fold change when calculating the ratio of fluorescence intense between the 2 groups. The elevated miRNAs included miR-290, miR-874, miR-292-5p, miR-327, miR-374, miR-98, miR-352, miR-132, miR-146b, and miR-196a. The down-regulated miRNAs included miR-145, miR-329, miR-375, miR-140*, and miR-29a. Validation of microarray assay by qRT-PCR showed similar results and the èž–èž–Ct value compared to the sham group are shown in Figure 1.
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