Detail

RLID: RLID00032367
RNA Symbol: hsa-miR-196b-5p
RNA Category: miRNA
Organism: Homo sapiens
Aliase: hsa-miR-196b
Sequence:
Homology: hsa-miR-196a-3p (Homo sapiens), hsa-miR-196a-5p (Homo sapiens)
Network:
Subcellular Localization:
Localization Tissue Validated Method PMID
Microvesicle Seminal Plasma Microarray 23539611
Description: MiRNAs shuttled by SMVs in seminal plasma are potent non-invasive biomarkers to evaluate defects originating from the different organs of the male reproductive tract, including the epididymis (Wang et al., 2011). In order to assess the reversibility of post-vasectomy miRNA sequelae, we investigated whether SMV miRNAs altered by vasectomy could be retrieved in SMVs from normospermic vasovasostomized donors. miRNA microarray profiling performed on SMVs from normal, vasectomized and vasovasostomized donors identified 313 miRNAs whose intensity was above the threshold of detection. Among these miRNAs, 293 were detected in samples from normal donors, 275 in vasectomized donors and 298 in vasovasostomized donors (Fig. 3, Supplementary data, Table SIV). Data are collected from Table S4.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00032362 Cytoplasm Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00032363 Extracellular vesicle HEK293T|HMEC-1|Mononuclear cell Next-generation sequencing 22849433
RLID00032364 Exosome Serum Microarray 18589210
RLID00032365 Exosome Brain tissue Microarray 23382797
RLID00032366 Microvesicle Plasma qRT-PCR 19002258
RLID00032368 Mitochondrion Skeletal muscular cell In situ hybridization|qRT-PCR 21637849
RLID00032369 Mitochondrion HeLa cell Next-generation sequencing 22984580
RLID00032370 Mitochondrion Eembryonic kidney cell Next-generation sequencing 22984580
RLID00032371 Nucleolus HeLa cell qRT-PCR 23940654
RLID00032372 Nucleus Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00032373 Nucleus HeLa cell Next-generation sequencing 22058130
RLID00032374 Exosome B cell Next-generation sequencing 25242326
RLID00032375 Exosome Serum Next-generation sequencing 24683445
RLID00032376 Exosome Plasma Next-generation sequencing 24683445