Detail

RLID: RLID00032848
RNA Symbol: hsa-miR-494-3p
RNA Category: miRNA
Organism: Homo sapiens
Sequence:
Homology: eca-miR-323-5p (Equus caballus), hsa-miR-1185-1-3p (Homo sapiens)
Network:
Subcellular Localization:
Localization Tissue Validated Method PMID
Microvesicle Seminal Plasma Microarray 23539611
Description: MiRNAs shuttled by SMVs in seminal plasma are potent non-invasive biomarkers to evaluate defects originating from the different organs of the male reproductive tract, including the epididymis (Wang et al., 2011). In order to assess the reversibility of post-vasectomy miRNA sequelae, we investigated whether SMV miRNAs altered by vasectomy could be retrieved in SMVs from normospermic vasovasostomized donors. miRNA microarray profiling performed on SMVs from normal, vasectomized and vasovasostomized donors identified 313 miRNAs whose intensity was above the threshold of detection. Among these miRNAs, 293 were detected in samples from normal donors, 275 in vasectomized donors and 298 in vasovasostomized donors (Fig. 3, Supplementary data, Table SIV). Data are collected from Table S4.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00032839 Circulating Serum Next-generation sequencing 23641832
RLID00032840 Circulating Follicular fluid Microarray 23666971
RLID00032841 Exosome Serum Microarray 18589210
RLID00032842 Exosome Breast cancer cell Microarray 20976003
RLID00032843 Exosome Dendritic cell Microarray 21505438
RLID00032844 Exosome B cell Microarray 21505438
RLID00032845 Exosome Malignant melanoma cell Microarray 23056502
RLID00032846 Exosome Brain tissue Microarray 23382797
RLID00032847 Exosome Breast cancer cell Microarray 24468161
RLID00032849 Microvesicle Follicular fluid Microarray 23666971
RLID00032850 Mitochondrion HeLa cell RT-PCR|Microarray 21695135
RLID00032851 Nucleolus HeLa|MCF7 Microarray 24918059
RLID00032852 Exosome Serum Next-generation sequencing 24683445
RLID00032853 Exosome Plasma Next-generation sequencing 24683445
RLID00032854 Mitochondrion HeLa cell Microarray|RT-PCR 21695135
RLID00032855 Exosome Mast cell Microarray 24009880