Detail

RLID: RLID00033065
RNA Symbol: hsa-miR-502-5p
RNA Category: miRNA
Organism: Homo sapiens
Aliase: hsa-miR-502
Sequence:
Homology: hsa-miR-500a-3p (Homo sapiens), hsa-miR-500a-5p (Homo sapiens)
Network:
Subcellular Localization:
Localization Tissue Validated Method PMID
Microvesicle Seminal Plasma Microarray 23539611
Description: MiRNAs shuttled by SMVs in seminal plasma are potent non-invasive biomarkers to evaluate defects originating from the different organs of the male reproductive tract, including the epididymis (Wang et al., 2011). In order to assess the reversibility of post-vasectomy miRNA sequelae, we investigated whether SMV miRNAs altered by vasectomy could be retrieved in SMVs from normospermic vasovasostomized donors. miRNA microarray profiling performed on SMVs from normal, vasectomized and vasovasostomized donors identified 313 miRNAs whose intensity was above the threshold of detection. Among these miRNAs, 293 were detected in samples from normal donors, 275 in vasectomized donors and 298 in vasovasostomized donors (Fig. 3, Supplementary data, Table SIV). Data are collected from Table S4.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00033060 Cytoplasm Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00033061 Exosome Serum Microarray 18589210
RLID00033062 Exosome Dendritic cell Microarray 21505438
RLID00033063 Exosome Malignant melanoma cell Microarray 23056502
RLID00033064 Exosome Brain tissue Microarray 23382797
RLID00033066 Nucleus Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00033067 Nucleus HeLa cell Next-generation sequencing 22058130
RLID00033068 Nucleus HeLa|MCF7 Microarray 24918059
RLID00033069 Microvesicle MSC cell qRT-PCR 20668554
RLID00033070 Microvesicle Liver stem cell qRT-PCR 20668554