Detail

RLID: RLID00033334
RNA Symbol: hsa-miR-575
RNA Category: miRNA
Organism: Homo sapiens
Sequence:
Subcellular Localization:
Localization Tissue Validated Method PMID
Exosome Breast cancer cell Microarray 20976003
Description: Because of the suggested roles of extracellular miRNAs in signaling and diagnosis, we investigated whether the intracellular and extracellular miRNA composition are the same. To answer this question, we performed microRNA microarray analyses of MCF7 cellular (c) and extracellular (x) RNAs (Figure 2A), and found that about 66% of the released miRNAs are at an abundance that closely reflects the cellular miRNA abundance (Figures 2B and 2C). This finding is in agreement with a model wherein most, but not all miRNAs are released passively by mass action. Data are collected from Figure 2.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00033335 Exosome B cell Microarray 21505438
RLID00033336 Exosome T cell Microarray 21505438
RLID00033337 Exosome Malignant melanoma cell Microarray 23056502
RLID00033338 Microvesicle Hepatoma cell qRT-PCR|Microarray 23771658