Detail
| RLID: | RLID00033645 |
| RNA Symbol: | hsa-miR-421 |
| RNA Category: | miRNA |
| Organism: | Homo sapiens |
| Subcellular Localization: | |
| Localization | Tissue | Validated Method | PMID |
| Nucleus | HeLa cell | Next-generation sequencing | 22058130 |
| Description: Here, we present a data set excluding these RNA before sequencing through locked nucleic acids (LNA), greatly increasing pre-miRNA sequence counts with no discernable effect on pre-miRNA or mature miRNA sequencing. Analysis of profiles generated in total, nuclear and cytoplasmic cell fractions reveals that pre-miRNAs are subject to a wide range of regulatory processes involving loci-specific 3'- and 5'-end variation entailing complex cleavage patterns with co-occurring polyuridylation. Data were collected from Supplementary file. | |||
Other Subcellular Localization:
| RLID | Localization | Tissue | Validated Method | PMID |
| RLID00033633 | Circulating | Cerebrospinal fluid | Next-generation sequencing|RT-PCR | 23525801 |
| RLID00033634 | Circulating | Serum | Next-generation sequencing|RT-PCR | 23525801 |
| RLID00033635 | Circulating | Gastric juice | - | 24456939 |
| RLID00033636 | Cytoplasm | Nasopharyngeal carcinoma cell | Next-generation sequencing | 20498841 |
| RLID00033637 | Extracellular vesicle | HEK293T|HMEC-1|Mononuclear cell | Next-generation sequencing | 22849433 |
| RLID00033638 | Exosome | Serum | Microarray | 18589210 |
| RLID00033639 | Exosome | Plasma | Next-generation sequencing | 23663360 |
| RLID00033640 | Microvesicle | Seminal Plasma | Microarray | 23539611 |
| RLID00033641 | Mitochondrion | Skeletal muscular cell | In situ hybridization|qRT-PCR | 21637849 |
| RLID00033642 | Mitochondrion | HeLa cell | Next-generation sequencing | 22984580 |
| RLID00033643 | Mitochondrion | Eembryonic kidney cell | Next-generation sequencing | 22984580 |
| RLID00033644 | Nucleus | Nasopharyngeal carcinoma cell | Next-generation sequencing | 20498841 |
| RLID00033646 | Exosome | Serum | Next-generation sequencing | 24683445 |
| RLID00033647 | Exosome | Plasma | Next-generation sequencing | 24683445 |
| RLID00033648 | Nucleus | HeLa|MCF7 | Microarray | 24918059 |