Detail

RLID: RLID00034346
RNA Symbol: hsa-miR-149-3p
RNA Category: miRNA
Organism: Homo sapiens
Aliase: hsa-miR-149*
Sequence:
Homology: hsa-miR-149-5p (Homo sapiens), mmu-miR-149-5p (Mus musculus)
Network:
Subcellular Localization:
Localization Tissue Validated Method PMID
Exosome Breast cancer cell Microarray 20976003
Description: Because of the suggested roles of extracellular miRNAs in signaling and diagnosis, we investigated whether the intracellular and extracellular miRNA composition are the same. To answer this question, we performed microRNA microarray analyses of MCF7 cellular (c) and extracellular (x) RNAs (Figure 2A), and found that about 66% of the released miRNAs are at an abundance that closely reflects the cellular miRNA abundance (Figures 2B and 2C). This finding is in agreement with a model wherein most, but not all miRNAs are released passively by mass action. Data are collected from Figure 2.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00034347 Exosome T cell Microarray 21505438
RLID00034348 Exosome B cell Microarray 21505438
RLID00034349 Exosome K562 cell Microarray 24460325
RLID00034350 Exosome Breast cancer cell RT-PCR|Microarray 24468161
RLID00034351 Mitochondrion Eembryonic kidney cell Next-generation sequencing 22984580
RLID00034352 Circulating Serum Next-generation sequencing 22719975