Detail

Localization	Tissue	Validated Method	PMID
Exosome	Breast cancer cell	Microarray	20976003
Description: Because of the suggested roles of extracellular miRNAs in signaling and diagnosis, we investigated whether the intracellular and extracellular miRNA composition are the same. To answer this question, we performed microRNA microarray analyses of MCF7 cellular (c) and extracellular (x) RNAs (Figure 2A), and found that about 66% of the released miRNAs are at an abundance that closely reflects the cellular miRNA abundance (Figures 2B and 2C). This finding is in agreement with a model wherein most, but not all miRNAs are released passively by mass action. Data are collected from Figure 2.

Other Subcellular Localization:

RLID	Localization	Tissue	Validated Method	PMID
RLID00034650	Circulating	Serum	Next-generation sequencing\|RT-PCR	23525801
RLID00034651	Circulating	Serum	Next-generation sequencing	23641832
RLID00034652	Circulating	Follicular fluid	Microarray	23666971
RLID00034653	Circulating	Serum	Next-generation sequencing	24904649
RLID00034654	Circulating	Serum	Next-generation sequencing	25359176
RLID00034656	Exosome	B cell	Microarray	21505438
RLID00034657	Exosome	T cell	Microarray	21505438
RLID00034658	Exosome	Plasma	Next-generation sequencing	23663360
RLID00034659	Microvesicle	Follicular fluid	Microarray	23666971
RLID00034660	Mitochondrion	Eembryonic kidney cell	Next-generation sequencing	22984580
RLID00034661	Exosome	Serum	Next-generation sequencing	24683445
RLID00034662	Microvesicle	A549\|HepG2	Microarrays\|RT-PCR	20615901
RLID00034663	Exosome	A549\|HepG2	Microarrays\|RT-PCR	20615901
RLID00034664	Exosome	Epithelial cell	-	22529849
RLID00034665	Exosome	Liver carcinoma cell	-	22529849
RLID00034666	Exosome	Ovarian tumor cell	-	22529849
RLID00034667	Circulating	Serum	Next-generation sequencing	22719975
RLID00034668	Exosome	Mast cell	Microarray	24009880