Detail

RLID: RLID00034777
RNA Symbol: hsa-miR-574-5p
RNA Category: miRNA
Organism: Homo sapiens
Sequence:
Homology: hsa-miR-574-3p (Homo sapiens), mmu-miR-574-3p (Mus musculus)
Network:
Subcellular Localization:
Localization Tissue Validated Method PMID
Exosome Breast cancer cell Microarray 20976003
Description: Because of the suggested roles of extracellular miRNAs in signaling and diagnosis, we investigated whether the intracellular and extracellular miRNA composition are the same. To answer this question, we performed microRNA microarray analyses of MCF7 cellular (c) and extracellular (x) RNAs (Figure 2A), and found that about 66% of the released miRNAs are at an abundance that closely reflects the cellular miRNA abundance (Figures 2B and 2C). This finding is in agreement with a model wherein most, but not all miRNAs are released passively by mass action. Data are collected from Figure 2.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00034773 Circulating Serum qRT-PCR 21258252
RLID00034774 Circulating Serum Microarray|qRT-PCR 22344312
RLID00034775 Circulating Serum Next-generation sequencing|RT-PCR 23525801
RLID00034776 Cytoplasm Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00034778 Exosome B cell Microarray 21505438
RLID00034779 Exosome Breast milk Next-generation sequencing 22211110
RLID00034780 Circulating Serum Microarray 23169280
RLID00034781 Exosome Plasma Next-generation sequencing 23663360
RLID00034782 Mitochondrion HeLa cell Next-generation sequencing 22984580
RLID00034783 Mitochondrion Eembryonic kidney cell Next-generation sequencing 22984580
RLID00034784 Nucleus Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00034785 Extracellular vesicle Colon Cancer Cell Line qRT-PCR|RNA-seq 25330373
RLID00034786 Circulating Serum Next-generation sequencing 22719975
RLID00034787 Exosome Mast cell Microarray 24009880