Detail

RLID: RLID00035389
RNA Symbol: hsa-miR-1268a
RNA Category: miRNA
Organism: Homo sapiens
Aliase: hsa-miR-1268
Sequence:
Subcellular Localization:
Localization Tissue Validated Method PMID
Exosome Breast cancer cell Microarray 20976003
Description: Because of the suggested roles of extracellular miRNAs in signaling and diagnosis, we investigated whether the intracellular and extracellular miRNA composition are the same. To answer this question, we performed microRNA microarray analyses of MCF7 cellular (c) and extracellular (x) RNAs (Figure 2A), and found that about 66% of the released miRNAs are at an abundance that closely reflects the cellular miRNA abundance (Figures 2B and 2C). This finding is in agreement with a model wherein most, but not all miRNAs are released passively by mass action. Data are collected from Figure 2.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00035387 Circulating Serum Next-generation sequencing 23641832
RLID00035388 Extracellular vesicle HEK293T|HMEC-1|Mononuclear cell Next-generation sequencing 22849433
RLID00035390 Exosome Malignant melanoma cell Microarray 23056502
RLID00035391 Exosome Breast cancer cell Microarray 24468161
RLID00035392 Microvesicle Seminal Plasma Microarray 23539611
RLID00035393 Mitochondrion HeLa cell Next-generation sequencing 22984580
RLID00035394 Mitochondrion Eembryonic kidney cell Next-generation sequencing 22984580