Detail

RLID: RLID00035439
RNA Symbol: hsa-miR-664a-3p
RNA Category: miRNA
Organism: Homo sapiens
Aliase: hsa-miR-664, hsa-miR-664-3p
Sequence:
Homology: hsa-miR-664a-5p (Homo sapiens), hsa-miR-664b-3p (Homo sapiens)
Subcellular Localization:
Localization Tissue Validated Method PMID
Microvesicle Seminal Plasma Microarray 23539611
Description: MiRNAs shuttled by SMVs in seminal plasma are potent non-invasive biomarkers to evaluate defects originating from the different organs of the male reproductive tract, including the epididymis (Wang et al., 2011). In order to assess the reversibility of post-vasectomy miRNA sequelae, we investigated whether SMV miRNAs altered by vasectomy could be retrieved in SMVs from normospermic vasovasostomized donors. miRNA microarray profiling performed on SMVs from normal, vasectomized and vasovasostomized donors identified 313 miRNAs whose intensity was above the threshold of detection. Among these miRNAs, 293 were detected in samples from normal donors, 275 in vasectomized donors and 298 in vasovasostomized donors (Fig. 3, Supplementary data, Table SIV). Data are collected from Table S4.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00035437 Cytoplasm Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00035438 Exosome Plasma Next-generation sequencing 23663360
RLID00035440 Mitochondrion Skeletal muscular cell In situ hybridization|qRT-PCR 21637849
RLID00035441 Nucleus Nasopharyngeal carcinoma cell Next-generation sequencing 20498841
RLID00035442 Nucleus HeLa cell Next-generation sequencing 22058130
RLID00035443 Microvesicle Colon Cancer Cell Line qRT-PCR|RNA-seq 25330373
RLID00035444 Exosome B cell Next-generation sequencing 25242326
RLID00035445 Exosome Serum Next-generation sequencing 24683445
RLID00035446 Exosome Plasma Next-generation sequencing 24683445