Detail

RLID: RLID00035577
RNA Symbol: hsa-miR-2110
RNA Category: miRNA
Organism: Homo sapiens
Sequence:
Subcellular Localization:
Localization Tissue Validated Method PMID
Circulating Plasma Next-generation sequencing 25415674
Description: To determine the effects of CAD on the levels of circulating miRNAs, we performed miRNA profile analysis by deep sequencing using RNA isolated from 20 patients with CAD and 20 healthy controls. Two hundred ninety-six miRNAs were detected in the plasma of healthy individuals and 196 in patients with CAD. Among all the miRNAs detected, 173 miRNAs were found in both groups, only 123 miRNAs were detected in healthy individuals, while only 23 miRNAs were detected in patients with CAD. The levels of circulating miRNA profoundly differed between patients and healthy controls, as demonstrated in the scatter (Figure ?(Figure1).1). There were 53 miRNAs that showed more than 2-fold differential expression between groups. Detailed information of these miRNAs is listed in supplementary Table 2.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00035568 Circulating Serum Next-generation sequencing|RT-PCR 23525801
RLID00035569 Circulating Serum Next-generation sequencing 23641832
RLID00035570 Extracellular vesicle HEK293T|HMEC-1|Mononuclear cell Next-generation sequencing 22849433
RLID00035571 Exosome Plasma Next-generation sequencing 23663360
RLID00035572 Microvesicle Seminal Plasma Microarray 23539611
RLID00035573 Mitochondrion Skeletal muscular cell In situ hybridization|qRT-PCR 21637849
RLID00035574 Mitochondrion HeLa cell Next-generation sequencing 22984580
RLID00035575 Mitochondrion Eembryonic kidney cell Next-generation sequencing 22984580
RLID00035576 Nucleus HeLa cell Next-generation sequencing 22058130
RLID00035578 Exosome Serum Next-generation sequencing 24683445
RLID00035579 Exosome Plasma Next-generation sequencing 24683445
RLID00035580 Circulating Serum Next-generation sequencing 22719975