Detail

RLID: RLID00036490
RNA Symbol: hsa-miR-128-1-5p
RNA Category: miRNA
Organism: Homo sapiens
Sequence:
Homology: hsa-miR-128-2-5p (Homo sapiens), hsa-miR-128-3p (Homo sapiens)
Network:
Subcellular Localization:
Localization Tissue Validated Method PMID
Exosome Breast cancer cell Microarray 20976003
Description: Because of the suggested roles of extracellular miRNAs in signaling and diagnosis, we investigated whether the intracellular and extracellular miRNA composition are the same. To answer this question, we performed microRNA microarray analyses of MCF7 cellular (c) and extracellular (x) RNAs (Figure 2A), and found that about 66% of the released miRNAs are at an abundance that closely reflects the cellular miRNA abundance (Figures 2B and 2C). This finding is in agreement with a model wherein most, but not all miRNAs are released passively by mass action. Data are collected from Figure 2.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00036488 Cytoplasm Neural progenitor cell qRT-PCR|Microarray 21363885
RLID00036489 Exosome Saliva Microarray 19627513
RLID00036491 Exosome Dendritic cell Microarray 21505438
RLID00036492 Mitochondrion Skeletal muscular cell In situ hybridization|qRT-PCR 21637849
RLID00036493 Nucleus HeLa cell Next-generation sequencing 22058130