Detail
| RLID: | RLID00011863 |
| RNA Symbol: | MALAT1 |
| RNA Category: | lncRNA |
| Organism: | Homo sapiens |
| Aliase: | HCN, LINC00047, NCRNA00047, NEAT2, PRO2853, mascRNA |
| Subcellular Localization: | |
| Localization | Tissue | Validated Method | PMID |
| Nucleus | HeLa cell|Kidney|Lung fibroblast | In situ hybridizationq|RT-PCR | 22078878 |
| Description: While Pc2 methylation appears to be the key determinant for relocation of growth control genes, based on a methylation/demethylation dependent switch in preference for TUG1 or NEAT2 interactions, respectively, we are tempted to speculate that other ncRNAs recognize covalent modifications of other gene-associated proteins, exerting their ncRNA scaffold functions in distinct subnuclear compartments to act as sensors for many regulated signaling pathways, and as modulators of 'reading' marks on histone tails for a variety of chromodomain-containing proteins and other histone code 'readers'. | |||
Other Subcellular Localization:
| RLID | Localization | Tissue | Validated Method | PMID |