Detail
| RLID: | RLID00009351 |
| RNA Symbol: | NEAT1 |
| RNA Category: | lncRNA |
| Organism: | Homo sapiens |
| Aliase: | LINC00084, NCRNA00084, TncRNA, VINC |
| Subcellular Localization: | |
| Localization | Tissue | Validated Method | PMID |
| Nucleus | HeLa cell | Immunoblotting|RT-PCR | 23835137 |
| Description: NEAT1_2 lncRNA may act as a scaffold of RNAs and RNA binding proteins in the nuclei of ALS motor neurons, thereby modulating the functions of ALS-associated RNA-binding proteins during the early phase of ALS. These findings provide the first evidence of a direct association between paraspeckle formation and a neurodegenerative disease, and may shed light on the development of novel therapeutic targets for the treatment of ALS. | |||
Other Subcellular Localization:
| RLID | Localization | Tissue | Validated Method | PMID |