Detail
| RLID: | RLID00018103 |
| RNA Symbol: | RNU2-1 |
| RNA Category: | snRNA |
| Organism: | Homo sapiens |
| Aliase: | RNU2, U2 |
| Subcellular Localization: | |
| Localization | Tissue | Validated Method | PMID |
| Nucleus | HeLa cell | In situ hybridization | 1530887 |
| Description: The localization of U1 and U2 small nuclear RNAs (snRNAs) has been examined by in situ hybridization using 2'-O-alkyl oligonucleotide probes. We have found that these snRNAs, which are essential for pre-mRNA splicing, localize in a speckled distribution, in addition to being present in three of four foci, in HeLa cell nuclei. However, in cells of defined passage, such as Detroit 551 and WI-38 fibroblasts, these snRNAs are concentrated in nuclear speckles, and foci are not observed. | |||
Other Subcellular Localization:
| RLID | Localization | Tissue | Validated Method | PMID |