Detail
| RLID: | RLID00000417 |
| RNA Symbol: | TG |
| RNA Category: | mRNA |
| Organism: | Capra hircus |
| Subcellular Localization: | |
| Localization | Tissue | Validated Method | PMID |
| Cytoplasm | Thyroids | Next-generation sequencing|qRT-PCR | 272676 |
| Description: In regard to subcellular distribution, the relative amount of the thyroglobulin mRNA sequences from the goiter in nuclear RNA was 42% of normal, in cytoplasmic RNA was 7% of normal, and in the membrane fraction was only 1-2% of normal. Our results suggest that the lack of thyroglobulin in these goiters is due to a defect in thyroglobulin mRNA which leads to aberrant processing and/or transport of it from its site of synthesis to the endoplasmic reticulum. | |||
Other Subcellular Localization:
| RLID | Localization | Tissue | Validated Method | PMID |