Detail
| RLID: | RLID00028388 |
| RNA Symbol: | hsa-miR-21-5p |
| RNA Category: | miRNA |
| Organism: | Homo sapiens |
| Aliase: | hsa-miR-21 |
| Subcellular Localization: | |
| Localization | Tissue | Validated Method | PMID |
| Exosome | Ascites | qRT-PCR | 21601258 |
| Description: Fig. 2. Biochemical marker analysis of exosomes. (A) Exosomes isolated from ascites or pleural effusions of tumor or LC patients were analyzed using the indi cated mAb followed by peroxidase-conjugated secondary antibody and ECL detection. 10 æ¸ g exosomes were applied per lane. Note that HSP70, ADAM10, Annexin-1 and CD9 are considered as general exosome markers. HLA-DR was used as a marker for immune cell derived exosomes. Note that in BrCa patients #9鈥?4 samples were derived from pleural effusions and #15 and 16 were from ascites. (B) The content of the indicated miRNAs was quantified by real-time RT-PCR in exosomes from ascites of OvCa (n=10) or LC patients (n=6) or BrCa pleural effusions (n=7). Note, that low Ct values re fl ect high expression levels of the respective miRNA. P-values in the fi gure are indicated as follows: * < 0.05, ** < 0.01 *** < 0.001. Data are collected from Figure 2. | |||
Other Subcellular Localization:
| RLID | Localization | Tissue | Validated Method | PMID |