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Detail

Detail

RLID: RLID00031620
RNA Symbol: hsa-miR-361-5p
RNA Category: miRNA
Organism: Homo sapiens
Aliase: hsa-miR-361
Homology: bta-miR-361 (Bos taurus), hsa-miR-361-3p (Homo sapiens)
Subcellular Localization:
Localization Tissue Validated Method PMID
Exosome Serum Next-generation sequencing 25349172
Description: Deep sequencing of the exosomal RNA extracted from serum samples was performed and sequences were mapped to miRBase Exosomal miRNA biomarkers for Alzheimer's disease. Approximately half of the reads obtained (43%) from small RNA sequencing corresponded with miRNA sequences (Supplementary Table 1). Overall, the sample cohort mapped to 1419 known human miRNA sequences (Supplementary Table 2). Following normalisation of reads and performing ANOVA analyses, 17 miRNA were found to be significantly deregulated (Figure 1); 14 miRNA were found to be upregulated (hsa-miR-361-5p, hsa-miR-30e-5p, hsa-miR-93-5p, hsa-miR-15a-5p, hsa-miR-143-3p, hsa-miR-335-5p, hsa-miR-106b-5p, hsa-miR-101-3p, hsa-miR-424-5p, hsa-miR-106a-5p, hsa-miR-18b-5p, hsa-miR-3065-5p, hsa-miR-20a-5p and hsa-miR-582-5p) and three miRNA were found to be downregulated (hsa-miR-1306-5p, hsa-miR-342-3p and 15b-3p; Table 2). Data are collected from Table 2.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID