Detail
Localization |
Tissue |
Validated Method |
PMID |
Circulating |
Plasma |
RT-PCR|Microarray |
23938262 |
Description: Plasma-based circulating MicroRNA biomarkers for Parkinson's disease. We identified 9 pairs of PD-predictive classifiers using k-TSP analysis and 13 most differentially-expressed miRNAs by SAM. A combination of both data sets produced a panel of PD-predictive biomarkers: k-TSP1 (miR-1826/miR-450b-3p), miR-626, and miR-505, and achieved the highest predictive power of 91% sensitivity, 100% specificity, 100% positive predicted value, and 88% negative predicted value in the replication set. However, low predictive values were shown in the validation set.
|
Other Subcellular Localization:
RLID |
Localization |
Tissue |
Validated Method |
PMID |